Excavators and cherry pickers moved onto the site at the weekend and began tearing apart garages and workshops, some of which were built more than 100-years ago.
The garages had been used to house and repair a fleet of 120 vehicles operated by Preston Bus, but the aging buildings were no longer considered fit for purpose.
Parent company Rotala said: “The existing garage facilities were erected in the early part of the 20th century and are not currently a safe working environment with potential vehicle movement hazards.”
But Rotala has given its assurance that the site will remain as a bus depot and will eventually be "redeveloped to suit the requirements of a 21st century public transport facility".
It also confirmed that the ornate stone building fronting onto Deepdale Road, built in 1914, will be preserved.
The cleared area will become a hardstanding for buses until redevelopment can take place at a future date.
We also took a last look round the depot before the demolition started. You can view our pictures here.