Fire crews tore the roof of an overturned car to free the man who was trapped inside after a crash with an on-call ambulance in Plungington Road at around 9.30am.
The casualty was rushed to Royal Preston Hospital with major trauma injuries, said the ambulance service. The two ambulance crew members were not injured.
Pictures from the scene show the wreck of the silver car which had rolled onto its side after the collision.
You can read our full report on the incident with statements from police and North West Ambulance Service here.
1. Preston ambulance crash in Plungington Road
Pictures from the scene show the overturned silver car with its roof torn open where firefighters rescued the injured driver Photo: Kelvin Stuttard
2. Preston Ambulance crash in Plungington Road
"The two ambulance crew members are shaken but unharmed," said North West Ambulance Service Photo: Plungington's Community PACT
3. Preston ambulance crash in Plungington Road
The casualty was trapped inside the silver car after it overturned and had to be freed by fire crews Photo: Plungington's Community PACT
4. Preston ambulance crash in Plungington Road
Anyone who witnessed the crash should call police on 101, quoting log 0357 of June 17, 2022 Photo: Kelvin Stuttard